Endocytosis (continued)

Mediated Endocytosis

If membrane invagination is triggered by the binding of a particular substance to a specific membrane constituent, it is a process of mediated endocytosis and is called that receptor constituent.

To enter the cell in this way it is necessary that the membrane has receptors specific to the substance in question.

This mechanism is used by many viruses (eg HIV) and toxins to penetrate the cell as over time they have developed a complementarity with the receptors.

This process is also important for medicine because they have been introduced into medicines used to destroy tumor cells fragments that bind to the specific membrane receptors of the cells to be destroyed.